Nuclear physics for next-generation cancer therapy
Prof. Dr. Marco Durante
Particle therapy is a rapidly growing and potentially the most effective and precise radiotherapy technique. However, physics research is needed to address a few problems that hamper its wider diffusion.
First, particle therapy is too expensive. Cheaper and smaller accelerators and beam delivery systems are necessary. Second, the position of the Bragg peak in the body is known with insufficient accuracy. Range uncertainties jeopardize the benefits of the sharp Bragg peak and force to use wide margins extending in the normal tissue. In addition, new detectors can improve imaging and dose monitoring while high-precision fragmentation measurements can improve transport codes used in treatment plans.
In this lecture we will give some examples of applications of nuclear physics to particle therapy. In particular, for reducing range uncertainty we will discuss the use of radioactive ion beams (RIBs) for simultaneous treatment and online range verification using positron emission tomography (PET). In this context, the ERC AdG BARB (Biomedical Applications of Radioactive ion Beams) project was initiated at GSI/FAIR aiming to assess the technical feasibility and investigate possible advantages of RIBs in preclinical studies.
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Location & approach
The campus of the Technical University of Dortmund is located near the freeway junction Dortmund West, where the Sauerland line A45 crosses the Ruhr expressway B1/A40. The Dortmund-Eichlinghofen exit on the A45 leads to the South Campus, the Dortmund-Dorstfeld exit on the A40 leads to the North Campus. The university is signposted at both exits.
The "Dortmund Universität" S-Bahn station is located directly on the North Campus. From there, the S-Bahn line S1 runs every 20 or 30 minutes to Dortmund main station and in the opposite direction to Düsseldorf main station via Bochum, Essen and Duisburg. In addition, the university can be reached by bus lines 445, 447 and 462. Timetable information can be found on the homepage of the Rhine-Ruhr transport association, and DSW21 also offer an interactive route network map.
One of the landmarks of the TU Dortmund is the H-Bahn. Line 1 runs every 10 minutes between Dortmund Eichlinghofen and the Technology Center via Campus South and Dortmund University S, while Line 2 commutes every 5 minutes between Campus North and Campus South. It covers this distance in two minutes.
From Dortmund Airport, it takes just over 20 minutes to get to Dortmund Central Station by AirportExpress and from there to the university by S-Bahn. A wider range of international flight connections is offered by Düsseldorf Airport, about 60 kilometers away, which can be reached directly by S-Bahn from the university's train station.
The facilities of TU Dortmund University are spread over two campuses, the larger Campus North and the smaller Campus South. Additionally, some areas of the university are located in the adjacent "Technologiepark".Zum Lageplan
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